This took me a while to figure out, so I’ll post it here in case someone else ever gets into this problem. After enabling WP Super Cache for a project at work, we’ve started seeing really weird and really random white page issues. WordPress would show a blank page and then a few minutes later it would start working again. But then it would disappear and so on and so forth.
Tracking the issue down, I’ve tweaked the WP Super Cache configuration quite a bit, but that didn’t help. And I was sure that it was related to WP Super Cache, since periods of appearing and disappearing were consistent with cache timeout settings. Browsing through WordPress support forums (threads one, two, and three) game an idea that it wasn’t just WP Super Cache on its own, but a combination of WP Super Cache plugin with something else on the system.
After a lengthy troubleshooting process, I think I nailed it. APC – an alternative PHP cache module – wasn’t friendly with WP Super Cache. So, as a short-term solution to the problem, I’ve disabled the APC and now everything seems to work well. I’m a bit busy now to troubleshoot the problem further, but if you have any idea of why that could be happening, please share.